In Trikala there are 2 departments of University of Thessaly: Department of Physical Education and Sport ScienceDepartment of Dietetics and Nutrition, There is also the Permanent Commissioned Officers School.

Trikala city is located in the center of Greece and covers an area of 3,384 km. The permanent population of the city is 61.653. The territory of the wider area is mainly mountainous (71.8% of the Regional Unity area), however the city is in the lowland. In the Regional Unit of Trikala the climate is continental.